Host Modulation Therapy for Periodontal Disease: Subantimicrobial-dose doxycycline, Medical as well as Dental Benefits
نویسنده
چکیده
Stephen Walker, M.Sc., Ph.D., Associate Professor, Department of Oral Biology and Pathology, School of Dental Medicine Stony Brook University, State University of New York Stony Brook, N.Y., U.S.A. And Lorne M. Golub, D.M.D., M.Sc., M.D. (honorary), S.U.N.Y. Distinguished Professor Department of Oral Biology and Pathology School of Dental Medicine Stony Brook University, State University of New York
منابع مشابه
Host response modulation in periodontics
Host response modulation (or host modulation) is a term that has been introduced to the dental profession relatively recently. In the periodontal context, and in very simple terms, it means modifying or modulating destructive or damaging aspects of the inflammatory host response that develops in the periodontal tissues as a result of the chronic challenge presented by the subgingival bacterial ...
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Host Modulation Therapy (HMT) is a treatment concept that reduces tissue destruction and stabilizes or even regenerates inflammatory tissue by modifying host response factors. It has been used for treating osteoporosis and arthritis for several decades. However, its use in dentistry has only been recently reported. The objective of this article is to present a review of the various literatures ...
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In this review, we critically evaluate the case-control studies examining the relationship between rheumatoid arthritis (RA) and periodontitis, two common chronic inflammatory diseases with a similar host-mediated pathogenesis. We review the "two-hit" periodontitis model that our group previously proposed, in which we elucidate how a systemic disease such as RA can potentially exacerbate or ini...
متن کاملEvaluation of subantimicrobial dose doxycycline as an adjunct to scaling and root planing in chronic periodontitis patients with diabetes: a randomized, placebo-controlled clinical trial.
AIM Diabetic patients have more severe periodontal destruction, but periodontal therapy can improve metabolic control. Recently, interest has focused on the use of subantimicrobial dose doxycycline (SDD) as a treatment paradigm. Therefore, this study was undertaken to evaluate clinical efficacy of SDD with scaling and root planning (SRP) in chronic periodontitis patients with diabetes. METHOD...
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A whole new light is emerging as we continue to learn more about periodontitis, one of the most interesting and baffling diseases. We are entering a new age as we look at periodontal disease from a different perspective. New modes of therapy have arrived, and laser treatment has expanded rapidly over the last several years. Treatment with locally administered antibiotics has become common. Util...
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تاریخ انتشار 2012